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Alternative Splicing Gallery

Detail view for swissprot protein HFE_HUMAN and isoform Q30201-8

Template: 1de4
Sequence Identity (Template - Swissprot): 1.0
Coverage of swissprot protein: 0.7816092

Alignment

HFE_HUMAN	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTV
1de4		-------------------------RSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTV
SSE		-------------------------CCEEEEEEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
VARSPLIC	                                                                                                    

HFE_HUMAN	DFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRG
1de4		DFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRG
SSE		HHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEEEEEECCEEEEEEEHHHCEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHCCCC
VARSPLIC	                                                                                                    

HFE_HUMAN	VLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
1de4		VLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIW---
SSE		CCCCCECCEEEEEEEECCCCEEEEEEEEEEECCCCEEEEEECCEECCHHHCCCCEEEECCCCCEEEEEEEEECCCCHHHEEEEEECCCCCCCEEECC---
VARSPLIC	                                                                          RRDDDDDDDDDDDDDDDDDDDDD   

HFE_HUMAN	PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
1de4		------------------------------------------------
SSE		------------------------------------------------
VARSPLIC

Varsplic events:
VSP_003227 REMOVE 277-348, affected aminoacids in template: 251-271 Color: Red
VSP_003226 REPLACE 275-276 GE => KY, affected aminoacids in template: 249-250 Color: Green

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