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Alternative Splicing Gallery

Detail view for swissprot protein HDAC8_MOUSE and isoform Q8VH37-2

Template: 1t69
Sequence Identity (Template - Swissprot): 0.97206706
Coverage of swissprot protein: 0.9496021

Alignment

HDAC8_MOUSE	MEMPEEPANSGHSLPPVYIYSPEYVSICDSLVKVPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIEYGLGY
1t69		-------------LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQ------PDSIEYGLGY
SSE		-------------CCCEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHCEEECCCCCCHHHHHCCCCHHHHHHHHHHCC------CCCCCCCCCC
VARSPLIC	                                                                                                    

HDAC8_MOUSE	DCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHHGDGVEDAFSFTSKVMTVSL
1t69		DCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
SSE		CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCECCECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEE
VARSPLIC	                                                                                                    

HDAC8_MOUSE	HKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQWQLATLI
1t69		HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
SSE		EECCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCECCCCCCCCCECHHHHHHHHHHHHCCCCEEEE
VARSPLIC	                                             RRRRRRRRDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

HDAC8_MOUSE	LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
1t69		LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
SSE		ECCCCCCHHHHHHHHHHHHHHHHCCCCCCECCCCCCHHHHCCCCECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

Varsplic events:
VSP_007179 REMOVE 254-377, affected aminoacids in template: 234-357 Color: Red
VSP_007178 REPLACE 246-253 SVLKEVYQ => RACFTRTP, affected aminoacids in template: 226-233 Color: Green

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